Kratom for Mental Health: How it Works?

Mental Health

Kratom has been more widely used in the west to treat pain and opioid addiction. However, several people who use Kratom use it for various reasons. 

One of the more popular reasons is mental health, mainly depression and anxiety.

One of the many effects of Kratom is mood. Even in Southeast Asia, workers use Kratom to make their hard work more accessible. This is because there’s a boost in energy and an uplifting spirit that comes with taking it.

If you’re curious about Kratom’s physiological and psychological effects, you’ve come to the right place. Keep reading to learn more!

What Is Kratom?

The tropical evergreen Mitragyna speciosa tree, also known as Kratom, is a native of Southeast Asia and a member of the coffee family. Indigenous peoples have historically utilized it as a stimulant to increase stamina and lessen weariness.

It has also been researched in conventional medicine for various ailments, such as pain and heroin addiction.

The plant’s leaves or an extract made from the leaves are used to make various products, including pills and liquids, that alleviate symptoms of depression, anxiety, opioid dependency, and chronic pain.

How Is It Used?

The majority of kratom users in a 2016 online survey of over 8,000 people who were primarily contacted through the AKA reported using the substance to treat mood disorders like sadness and anxiety or to relieve pain.

Kratom is traditionally chewed or drank as tea. Resins, extracts, and tinctures are other forms of Kratom. Kratom can be purchased over the counter in beverages, pills, capsules, and powders.

For instance, a mixture of kratom leaves, cough syrup, cola, and ice can be purchased in Thailand. However, Kratom is typically taken as pills or a powder that is dissolved into a beverage.

Whether you’re using Kratom already, check out Oasis Kratom and Nuwave Botanicals for affordable kratom products.

Kratom For Anxiety and Depression

So, how does Kratom help your mood? According to a report, many people use the drug daily or multiple times each day to alleviate concerns about depression and anxiety. They feel better because Kratom alters their mood and gives them the energy to cope.

The participants’ usage of the substance to treat their depression is based on their subjective reports and not on professional psychiatric evaluations of the subjects.

Kratom for anxiety claims that the effects typically start five to ten minutes after consuming the substance and last about two hours. Less frequent doses will last longer.

Mental Health

The Science Behind Kratom

The indole alkaloids are just one of the many substances this plant possesses. Twenty-five of these alkaloids has been named thus far. Mitragynine, the primary alkaloid, and 7-hydroxy mitragynine are responsible for most psychoactive effects. 

Because of the wide range of plant and environmental conditions that affect the quantities of these 25 alkaloids, different plants have different potencies and physical characteristics.

Mitragynine has the potential to be stimulating at modest doses. At higher doses, it can resemble a sedative. Potentially explaining its anxiolytic and depressive effects is its capacity to block pain by attaching to opioid receptors in the brain.

According to a 2017 review, Kratom can improve mood and reduce anxiety in certain users. This review mentions an older rodent study that demonstrated a decrease in corticosterone. In humans, cortisol is the identical hormone.

The same research implies that Kratom may have sedative properties.

Are There Any Side Effects or Dangers?

Various variables, including dose, strain, and maybe others, influence how Kratom will affect a given individual. Remember that study on this topic is ongoing.

When consumed orally, Kratom can have various adverse side effects, including thyroid issues, anger, dry mouth, frequent urination, constipation, and hallucinations.

Out of 660 calls to poison control centers about kratom exposure in a 2016 CDC report, most reported adverse effects were mild to moderate.

Possibility Of Become Dependent

The risks of tolerance, dependency, and withdrawal are associated with Kratom. People who use Kratom may develop a tolerance or the need to use more of the substance to get the intended result.

In Southeast Asia, where Kratom is a native plant, dependency sets in for 55% of regular users in as little as three months. New users of Kratom report a 10-fold increase in dose within the initial few weeks due to tolerance.

When they stop using it, they may experience withdrawal symptoms.

Withdrawal Symptoms

Regular users of Kratom who quit using it all of a sudden may have various unpleasant symptoms, including fever, hot flashes, diarrhea, twitching, watery eyes, anxiety, insomnia or restlessness, negative mood swings, tension, hostility, and restlessness.

Kratom Interactions With Other Medications Or Substances

When Kratom is taken with other substances and prescription medications, the side effects may become considerably more severe.

Some kratom compounds have been shown to affect how the liver metabolizes other medicines, resulting in hazardous interactions. From seizures to liver damage, several drug interactions could have adverse effects.

The liver modifies and breaks down several drugs. Kratom may slow down the rate at which the liver metabolizes some drugs.

Some drugs’ effects and adverse effects, which are altered by the liver, may be exacerbated if Kratom is also taken. If you take any medications that are affected by the liver, consult your doctor before using Kratom.

Additionally, some drugs and vital substances react with Kratom, which may cause fatality. It’s a widely held assumption that kratom-related deaths are incredibly unlikely, if not outright impossible.

There are some reports of deaths. However, most of them saw co-ingestions with opioids, other substances, or contaminants in the case of kratom supplements.


In conclusion, Kratom is a tree native to Southeast Asia with several uses, including treating pain and opioid addiction and boosting energy levels and mood.

It is commonly used through pills or powders of the extract of the kratom plant. However, it may also be used in many other contexts.

People use Kratom to treat their depression and anxiety because it makes the everyday struggles of life seem a little easier to handle.

Kratom can improve mood and reduce anxiety in certain users thanks to mitragynine and 7-hydroxy mitragynine because it may decrease cortisol in humans.

Some side effects come with taking Kratom; however, they’re relatively mild and tolerable.

Though there is a possibility of becoming dependent and building tolerance, as a result, those who stop taking Kratom immediately may experience withdrawal symptoms.

Kratom users should also be aware of the interaction of Kratom with certain medicines because it may cause issues in the liver, seizures, etc.

Another risk of taking Kratom with other medications or vital substances is that it may cause fatalities when combined.


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